ĭuring the last 15 years, lens extraction, both cataract and clear lenses, has gained popularity, and a consistent amount of studies have shown the beneficial role of phacoemulsification (PE) and intraocular lens (IOL) implantation for the treatment of PACG. Compared to primary open-angle glaucoma, PACG is more likely to result in irreversible blindness if not adequately treated. The worldwide prevalence of primary angle-closure glaucoma (PACG) is estimated to increase from 20 to 32 million in 2040. In this group of patients, a careful preoperative endothelial evaluation should be performed.
In our population of PAC patients, XS is significantly associated with ECD change. PE in angle closure causes a significant ECD reduction. In the multivariate regression model, after correction for age and lens status, XS was the only parameter associated with ECD percentage change ( B = −36.00 ). The mean (SD) ECD (cells/mm 2) changed from 2275 (463) preoperatively to 1964 (613) postoperatively with a mean reduction of −310 (95% CI −445 to −176; ).
Coexistence of exfoliation syndrome (XS) was observed in 4 cases (9.1%).
The mean (SD) patient age was 71.6 (10.2) years; thirty-one (70.5%) of them were women. 44 patients with PAC were included in the study. The change in ECD and its relation to clinical characteristics and biometric parameters were evaluated by linear regression analysis. Anterior segment biomicroscopy and gonioscopy were also performed. In this prospective case series, ECD was evaluated by noncontact specular microscopy and biometric parameters by both noncontact optical biometry and anterior segment optical coherence tomography, preoperatively and at 12 months after surgery. To investigate demographic and anatomical factors associated with a reduction in endothelial cell density (ECD) after phacoemulsification (PE) for the treatment of primary angle closure (PAC).
0 kommentar(er)
